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Intramuscular (IM) injections go deeper, directly into the muscle tissue

Preclinical studies have reported that Exendin-4 (Ex-4) and dulaglutide display inhibitory effects on breast cancer, whereas liraglutide presents a trend of increased breast cancer incidence, with the risk ratio rising with prolonged exposure

In cases where the MIE is unknown or undefined, the earliest known KE in the chain (i.e., furthest upstream) should be used in lieu of the MIE and it should be made clear that the stated event is a KE and not the MIE